The Reason Why You Feel More Anxious When Using THC & How THC Can Aggervate Anxiety

Posted by Masterpiece Perham on Jul 6th 2025

The Reason Why You Feel More Anxious When Using THC & How THC Can Aggervate Anxiety

Why THC May Not Be the Best Solution for Anxiety: Exploring Better Alternatives

Cannabis, particularly THC (tetrahydrocannabinol), is often touted as a remedy for anxiety. However, for many individuals, using THC can actually exacerbate feelings of anxiety rather than alleviate them. This misconception stems from a misunderstanding of how THC interacts with the brain and body. While it does have medicinal benefits for certain conditions, THC is far from an ideal long-term solution for managing anxiety. Instead, other natural alternatives like kratom, kava, ashwagandha, rhodiola, and magnesium often provide far more effective and sustainable relief.

In this article, we’ll break down why THC can lead to increased anxiety, explore its physiological effects, and present better options for addressing anxiety, depression, and pain.


How THC Can Cause or Worsen Anxiety

While some people may feel a temporary sense of calm when using THC, others report increased anxiety, paranoia, and even panic attacks. These effects are tied to how THC interacts with the endocannabinoid system and other physiological processes in the body.

1. Elevated Cortisol Levels

THC use has been shown to increase levels of cortisol, the body's primary stress hormone. Elevated cortisol can lead to symptoms such as:

  • Increased heart rate.
  • Restlessness or jitteriness.
  • A feeling of being "on edge."
    This heightened cortisol response mimics the body's natural reaction to stress, which can make anxiety worse rather than better.

A study published in Drug and Alcohol Dependence (2017) found that frequent cannabis use is associated with dysregulated cortisol levels, which can contribute to higher stress and anxiety over time.

2. Overstimulation of CB1 Receptors

THC binds to CB1 receptors in the brain, which are part of the endocannabinoid system. While this interaction can create a euphoric or calming effect in small doses, overstimulation of these receptors—especially with high doses of THC—can lead to:

  • Feelings of paranoia.
  • Racing thoughts.
  • Heightened sensitivity to stimuli, which can feel overwhelming.

This overstimulation can mirror the symptoms of an anxiety attack, leaving users feeling worse instead of better.

3. Increased Heart Rate

THC is known to cause tachycardia (increased heart rate) in many users. For individuals already prone to anxiety, a racing heart can trigger or intensify feelings of panic. This physiological response can make it difficult to distinguish between THC-induced effects and true anxiety, leading to a vicious cycle of worry and discomfort.

4. Long-Term Effects on Mental Health

Chronic THC use can alter the brain's natural production of endocannabinoids, potentially leading to dependence on external cannabinoids to regulate mood. Over time, this can result in:

  • Increased baseline anxiety.
  • Difficulty focusing or concentrating.
  • Worsened symptoms of ADHD.

Many individuals who quit cannabis report improved mental health, including reduced anxiety, better focus, and a greater sense of emotional stability.


Better Alternatives for Anxiety Relief

If THC isn't the ideal solution for anxiety, what is? Several natural remedies have been shown to provide effective and sustainable relief from anxiety without the negative side effects associated with cannabis. Here’s a closer look at some of the best options:

1. Kratom

Kratom, a natural herb derived from the leaves of the Mitragyna speciosa tree, is gaining popularity for its ability to manage pain and anxiety.

  • How It Works: Kratom interacts with opioid receptors in the brain, providing pain relief and a sense of calm without the risks of traditional opioids.
  • Benefits: In small doses, kratom can boost mood and reduce anxiety, while higher doses offer sedative effects.

2. Kava

Kava, a root traditionally used in Pacific Island cultures, is a powerful natural anxiolytic.

  • How It Works: Kava promotes relaxation by enhancing GABA activity in the brain, which helps to calm the nervous system.
  • Benefits: Unlike THC, kava does not cause paranoia or increase heart rate, making it a safer option for anxiety relief.

3. Ashwagandha

Ashwagandha is an adaptogen that helps the body manage stress.

  • How It Works: It reduces cortisol levels, promoting a sense of calm and reducing symptoms of anxiety and stress.
  • Benefits: Ashwagandha is particularly effective for individuals with chronic stress or generalized anxiety disorder (GAD).

4. Rhodiola Rosea

Rhodiola is another adaptogen known for its ability to combat stress and fatigue.

  • How It Works: It improves serotonin and dopamine regulation, enhancing mood and reducing anxiety.
  • Benefits: Rhodiola not only reduces anxiety but also enhances focus and energy levels.

5. Magnesium

Magnesium plays a crucial role in regulating the nervous system.

  • How It Works: It helps to calm overactive nerves and supports healthy GABA function.
  • Benefits: Magnesium supplementation has been shown to reduce symptoms of anxiety, especially in individuals with magnesium deficiency.

Mushroom Extracts for Anxiety and Depression

Certain mushroom extracts, such as lion's mane and reishi, are emerging as powerful tools for mental health.

  • Lion’s Mane: Stimulates the production of nerve growth factor (NGF), which supports brain health and reduces symptoms of depression and anxiety.
  • Reishi: Known as the "mushroom of immortality," reishi helps to regulate cortisol levels and promote relaxation.

These natural remedies work by supporting the brain’s serotonin and dopamine systems, offering a more balanced approach to mental health than THC.


THC Has Its Place, But Not for Anxiety

To be clear, THC does have legitimate medicinal uses. It can be effective for:

  • Managing chronic pain.
  • Improving appetite in individuals with conditions like cancer or HIV/AIDS.
  • Helping with insomnia in the short term.

For recreational use, THC is often considered a safer alternative to alcohol, as it doesn’t carry the same risks of liver damage or addiction. However, when it comes to long-term anxiety management, THC is far from ideal and can often make the problem worse.


The Benefits of Quitting THC

Many individuals who stop using THC report significant improvements in their mental and physical health, including:

  • Reduced anxiety and paranoia.
  • Improved focus and productivity.
  • Better sleep quality.
  • Reduced symptoms of ADHD.

Quitting THC allows the brain to restore its natural balance of endocannabinoids, leading to a greater sense of calm and emotional stability.


Conclusion

While THC has its time and place, it’s not a sustainable or effective solution for anxiety. Elevated cortisol, overstimulation of CB1 receptors, and increased heart rate can all contribute to feelings of anxiety and make the problem worse over time. For those seeking long-term relief, natural alternatives like kratom, kava, ashwagandha, rhodiola, and magnesium offer far more effective and holistic solutions. Additionally, mushroom extracts like lion’s mane and reishi provide powerful support for mental health by promoting serotonin and dopamine production.

If you’re struggling with anxiety, consider exploring these natural remedies and consult with a healthcare professional to find the best option for your needs.